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Home / Primary Antibodies / Monoclonal Antibodies

anti-human CD279(PD-1)

SKU : BHA14700116

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Ancell Corporation

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Mfr.No.	279, 279-020, 279-030, 279-040, 279-820
Background	Human CD279 (PD-1, Programmed death 1) is a 55 kd Ig superfamily member with sililarity to CD28 andCD152(CTLA-4). It is expressed on activated T and B and myeloid cells, and engagement by its ligands PD-L1 (CD274, B7-H1) or PD-L2 (B7-DC) can inhibit proliferation and cytokine expression. In mice blockade of PD-1 ligand interaction has been used to augment T cell anti cancer responses (3,4,5). Anti-CD279 antibody clone ANC4H6 binds to CD279 present on PHA activated PBMC in FACS, and binds to recombinant CD279 in EIA. Pre incubation of recombinant CD279-coated plates with ANC4H6 blocks binding of biotinylated recombinant CD273 in EIA.
Formulation	50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate
Isotype	IgG1k
Reactivity	Human
Specificity	human

Purity	Antibody was Protein A purified from (low FBS containing) tissue culture supernatant. Purity was >95% Immunoglobulin by SDS-PAGE and contains less than 1% Bovine Immunoglobulin.
Storage	Store at 2 - 5°C. Freeze/Thawing is not recommended.
Storage Buffer	50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5 mg/ml Gentamicin Sulfate (as a preservative).

Applications	EIA, FC

Product Manual	Data Sheet

No Description Available.

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Combination SKU	Supplier No.	Conjugate	Size	Your price	Quantity
BHA14700116-1	279-020	Pur WA	100 ug	$200		Add to Cart
BHA14700116-2	279-030	Biotin	100 ug	$235		Add to Cart
BHA14700116-3	279-040	FITC	120 tests	$235		Add to Cart
BHA14700116-4	279-820	Pur/PF	100 ug	$200		Add to Cart

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