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Home / Primary Antibodies / Polyclonal Antibodies

CNOT8 antibody

SKU : BHA10801806

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Mfr.No.	FNab01812
Alternative Names	CALIF ; POP2
Categories	Primary Antibodies
Clonality	polyclonal
Description	Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.
Host	Rabbit
Immunogen	CCR4-NOT transcription complex, subunit 8
Isotype	IgG
Molecular Weight	34 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	CALIF, POP2

Uniprot	Q9UFF9
Gene Id	9337
Research Area	Epigenetics, Metabolism

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Manual	FNab01812.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801806	FNab01812	100ug	$240		Add to Cart

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