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Home / Primary Antibodies / Chip Antibodies

Acetyl-HIST1H4A (K16) Antibody

SKU : BHA10535067

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-PA010429PA16acHU
Alternative Names	Histone H4, HIST1H4A; HIST1H4B; HIST1H4C; HIST1H4D; HIST1H4E; HIST1H4F; HIST1H4H; HIST1H4I; HIST1H4J; HIST1H4K; HIST1H4L; HIST2H4A; HIST2H4B; HIST4H4, H4/A H4FA; H4/I H4FI; H4/G H4FG; H4/B H4FB; H4/J H4FJ; H4/C H4FC; H4/H H4FH; H4/M H4FM; H4/E H4FE; H4/D H4FD; H4/K H4FK; H4/N H4F2 H4FN HIST2H4; H4/O H4FO;
Categories	Primary Antibodies
Clonality	polyclonal
Description	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Host	Rabbit
Immunogen	Peptide sequence around site of Acetyl-Lys (16) derived from Human Histone H4
Involvement In Disease	Chromosomal aberrations involving HISTONE H4 is a cause of B-cell non-Hodgkin lymphomas (B-cell NHL). Translocation t(3;6)(q27;p21), with BCL6.
Isotype	IgG
Raised In	Rabbit
Reactivity	Human
Regulatory	RUO
Relevance	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Species	Homo Sapiens (Human)
Subcellular Location	Nucleus, Chromosome

Uniprot	P62805
Gene Id	554313
Database Links	HGNC:4781 OMIM:142750 KEGG:hsa:121504 STRING:9606.ENSP00000367034 UniGene:Hs.143080
Function	Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Protein Families	Histone H4 family
Research Area	Epigenetics and Nuclear Signaling
Weight	11,367 Da

Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form	Liquid
Format	Liquid
Purification	Antigen Affinity Purified
Purity	Antigen Affinity Purified
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Applications	ELISA, ChIP
Description	ELISA ; ChIP, ChIP ; ELISA
Tested Application	ELISA, ChIP

Datasheet
ELISA Protocol
Native Chromatin Immunoprecipitation(ChIP) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10535067	CSB-PA010429PA16acHU	100ul	$319		Add to Cart
BHA10535067	CSB-PA010429PA16acHU	50ul	$175		Add to Cart

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