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Home / Cells / Cell Lines

TMIGD2/NFAT Luciferase Reporter Jurkat Cell Line

SKU : BHC18200103

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BPS Bioscience

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Mfr.No.	78323
Description	Recombinant Jurkat cell line expressing firefly luciferase under the control of an NFAT response element, and with constitutive expression of human TMIGD2 (Transmembrane and immunoglobulin domain containing 2; CD28H; NM_144615). Expression of the firefly luciferase gene is driven by NFAT response elements located upstream of the minimal TATA promoter. Activation of the NFAT signaling pathway in these cells can be monitored by measuring luciferase activity. Mycoplasma testing: The cell line has been screened to confirm the absence of Mycoplasma species. Host Species: human Supplied as Each vial contains>1 x 106 cells in 1 ml of Cell Freezing Medium (Biohippo, #79796)
Background	HHLA2 (B7-H7) mediates an immune-stimulatory signal via TMIGD2 in naive T cells while it delivers an immune-inhibitory signal through KIR3DL3 (Killer Cell Immunoglobulin Like Receptor, Three Ig Domains and Long Cytoplasmic Tail 3) in activated T cells and Natural Killer (NK) cells.
Application	Characterize the biological activity of TMIGD2 interaction with B7-H7 Screen for B7-H7 antibodies in co-culture with B7-H7-expressing cells
Host Cell	Jurkat
Uniprot	Q96BF3
Synonyms	TMIGD2, Transmembrane and immunoglobulin domain-containing protein 2, CD28 homolog, Immunoglobulin and proline-rich receptor 1, IGPR-1, CD28H, IGPR1, UNQ3059/PRO9879
Shipping Temperature	-80°C (dry ice)
Note	License Disclosure: Visit Biohippobioscience.com/license for the label license and other key information about this product. Troubleshooting Guide: Visit Biohippobioscience.com/lentivirus-faq for detailed troubleshooting instructions. For all further questions, please email [email protected] Warning: Avoid freeze/thaw cycles.

Storage Stability	Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHC18200103	78323	2 vials	$11374		Add to Cart

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