Human Caucasian colon adenocarcinoma. Derived from a grade III adenocarcinoma of the colon of an 81 year old Caucasian female. The cells synthesise relatively large amounts of CEA (2, 000ng/1, 000, 000 cells in 21 days).Br /;The cells are positive for keratin by immunoperoxidase staining. The line is positive for expression of c-myc, K-ras, H-ras, N-ras, myb and fos oncogenes. N-myc and sis oncogene expression were not detected.