Recombinant clonal stable CHO cell line constitutively expressing full length human ROR1 protein (Genbank NM_005012.3). Surface expression of ROR1 was confirmed by flow cytometry. Each stable clonal cell line was selected for different levels of ROR1 [removed]High, Medium, Low) to mimic different stages of cancer target cells with various ROR1 expression levels.
Mycoplasma testing: This cell line has been screened using the Quick Test Mycoplasma Detection Kit (Biotool.com, #B39032) to confirm the absence of Mycoplasma contamination.
Host Species: hamster
Supplied as Each vial contains ~ 2.5 x 10^6 cells in 1 ml of Thaw Medium 3 + 10% DMSO.
Background
Tyrosine-protein kinase transmembrane receptor (ROR1) is an enzyme that in humans is encoded by the ROR1 gene. The ROR1 is expressed by tumor cells of various hematologic and solid malignancies and is largely absent from postnatal healthy cells and tissues. Treatment with a humanized monoclonal antibody specific for ROR1 (UC-961) can inhibit the capacity of ovarian cancer cells to migrate or engraft immune-deficient mice.
LICENSE DISCLOSURE: Purchase of this cell line grants you with a 10-year license to use this cell line in your immediate laboratory, for research use only. This license does not permit you to share, distribute, sell, sublicense, or otherwise make the cell line available for use to other laboratories, departments, research institutions, hospitals, universities, or biotech companies. The license does not permit the use of this cell line in humans or for therapeutic or drug use. The license does not permit modification of the cell line in any way. Inappropriate use or distribution of this cell line will result in revocation of the license and result in an immediate cease of sales and distribution of Biohippo products to your laboratory. Biohippo does not warrant the suitability of the cell line for any particular use, and does not accept any liability in connection with the handling or use of the cell line. Modifications of this cell line, transfer to another facility, or commercial use of the cells may require a separate license and additional fees; contact [email protected] for details. Publications using this cell line should reference Biohippo Inc. Warning: Avoid freeze/thaw cycles.
Storage Stability
Store in liquid nitrogen immediately upon receipt.