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PAI-1 Reporter (Luc) - Mv1 Lu Cell Line

SKU : BHC18200034

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BPS Bioscience

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Mfr.No.	60544
Description	PAI-1 Reporter (Luc)-Mv1 Lu cell line is designed for monitoring transforming growth factor beta (TGF-beta)-induced plasminogen activator inhibitor-1 (PAI-1) expression. Transforming growth factor-beta (TGF-beta) is a potent regulator of cellular differentiation, proliferation, migration, and protein expression.PAI-1 Reporter (Luc) -Mv1 Lu cell line contains a firefly luciferase gene under the control of PAI-1 responsive elements stably integrated into Mv1 Lu (NBL-7) cells, showing TGF-beta pathway response. This cell line is validated for the TGF-beta response to the induction of PAI-1 gene expression through luciferase activity. Mycoplasma testing: The cell line has been screened using the PCR-based VenorGeM Mycoplasma Detection kit (Sigma-Aldrich, #MP0025) to confirm the absence of Mycoplasma species. Host Species: Aleutian mink Supplied as Each vial contains ~ 2 x 10^6 cells in 1 ml of 10% DMSO.
Application	Monitor TGF-beta signaling pathway activity.
Host Cell	Mv1 Lu
Shipping Temperature	-80°C (dry ice)
Note	License Disclosure: Purchase of this cell line grants you with a 10-year license to use this cell line in your immediate laboratory, for research use only. This license does not permit you to share, distribute, sell, sublicense, or otherwise make the cell line available for use to other laboratories, departments, research institutions, hospitals, universities, or biotech companies. The license does not permit the use of this cell line in humans or for therapeutic or drug use. The license does not permit modification of the cell line in any way. Inappropriate use or distribution of this cell line will result in revocation of the license and result in an immediate cease of sales and distribution of Biohippo products to your laboratory. Biohippo does not warrant the suitability of the cell line for any particular use, and does not accept any liability in connection with the handling or use of the cell line. Modifications of this cell line, transfer to another facility, or commercial use of the cells may require a separate license and additional fees; contact [email protected] for details. Publications using this cell line should reference Biohippo Inc. Warning: Avoid freeze/thaw cycles.

Storage Stability	Store in liquid nitrogen immediately upon receipt.

Reference	Abe, M. et al. (1994) An assay for transforming growth factor- beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct. Analytical Biochemistry 216:276-584.Khan, S. et al. (2012) Quantification of active and total transforming growth factor-beta levels in serum and solid organ tissues by bioassay. BMC Research Notes 5: 636

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SKU	Supplier No.	Size	Your price	Quantity
BHC18200034	60544	2 vials	$3954.50		Add to Cart

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