JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
[email protected]

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Cells / Cell Lines

LILRB4 NFAT-Luciferase Reporter Jurkat Recombinant Cell Line

SKU : BHC18200209

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Request More Infos

BPS Bioscience

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

[email protected]

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	79750
Description	Recombinant Jurkat cells constitutively expressing human LILRB4 (Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 4, GenBank Accession #NM_001278426) and the firefly luciferase gene under the control of NFAT response elements. Host Species: human Supplied as Each vial contains 2 x 10^6 cells in 1 ml of FBS with 10% DMSO.
Background	Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 4 (LILRB4) contains multiple Immunoreceptor Tyrosine-based Inhibitory Motifs (ITIMs). LILRB4 expression on Acute Myeloid Leukemia (AML) cells promotes tumor cell infiltration and suppresses T cell activity. Because LILRB4 is highly expressed on AML cells but not on normal hematopoietic stem cells, LILRB4 has been identified as a promising therapeutic target for CAR-T cells.
Application	Screen for novel ligands of LILRB4
Host Cell	Jurkat
Synonyms	Eukocyte Immunoglobulin Like Receptor B4, CD85K
Shipping Temperature	-80°C (dry ice)
Note	License Disclosure: Purchase of this cell line grants you with a 10-year license to use this cell line in your immediate laboratory, for research use only. This license does not permit you to share, distribute, sell, sublicense, or otherwise make the cell line available for use to other laboratories, departments, research institutions, hospitals, universities, or biotech companies. The license does not permit use of this cell line in humans or for therapeutic or drug use. The license does not permit modification of the cell line in any way. Inappropriate use or distribution of this cell line will result in revocation of the license and result in an immediate cease of sales and distribution of Biohippo products to your laboratory. Biohippo does not warrant the suitability of the cell line for any particular use, and does not accept any liability in connection with the handling or use of the cell line. Modifications of this cell line, transfer to another facility, or commercial use of the cells may require a separate license and additional fees; contact [email protected] for details. Publications using this cell line should reference Biohippo Inc. Warning: Avoid freeze/thaw cycles.

Storage Stability	Immediately upon receipt, store vials in liquid nitrogen.

Reference	1. LILRB4 signaling in leukemia cells mediates T cell suppression and tumor infiltration. Deng M, et al. Nature. 2018. 562(7728):605-609.2. A novel anti-LILRB4 CAR-T cell for the treatment of monocytic AML. John S, et al. Mol Ther. 2018. 26(10):2487-2495.

Product Manual	Datasheet

Have you used this product?

Rate it now..!!

Login to Review

SKU	Supplier No.	Size	Your price	Quantity
BHC18200209	79750	2 vials	$10857		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2024 Biohippo. All rights reserved.