Human NF-kB/SEAP reporter cell line is not only useful in helping with the identification of pro or anti-inflammatory substances, but also can help to assay for proteasome activity since the activation of NF-kB results in the degradation of IkB through the proteasome-dependant pathway. The recombinant form of placental alkaline phosphatase (secreted alkaline phosphatase, SEAP) is used for reporter gene function.
Categories
Transfected Stable Cell Lines
Application
For research use only
Host Cell
HEK293
Species
Human
Shipping
Dry Ice
Storage
Liquid Nitrogen
Reviews of Human NF-kB/SEAP reporter cell line-HEK293