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GPRC5D (Cynomolgus) HEK293 Cell Line

SKU : BHC18200116

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Mfr.No.	78346
Description	Recombinant HEK293 cells expressing cynomolgus monkey (Macaca fascicularis) GPRC5D (the orphan G protein-coupled receptor, class C group 5 member D, accession #XP_005570250.1) under the control of a CMV promoter. Mycoplasma testing: The cell line has been screened to confirm the absence of Mycoplasma species. Host Species: human Supplied as Each vial contains 2 x 10⁶ cells in 1 ml of 10% DMSO
Background	The orphan G protein-coupled receptor, class C group 5 member D (GPRC5D) is a retinoic acid-inducible protein with seven transmembrane segments and a short N-terminal extracellular region. The strong and selective expression of GPRC5D in Multiple Myeloma cells, similar to the expression pattern of B-cell maturation antigen (BCMA), makes it a promising target for the treatment of Multiple Myeloma. It is anticipated that GPRC5D will be an alternative CAR T cell target for Multiple Myeloma immunotherapy.
Application	1. Cynomolgus monkey GPRC5D binding assays; screen for GPRC5D ligands and or antibodies. 2. Target cells for anti-GPRC5D CAR-T development.
Formulation	For best results, it is highly recommended to use these validated and optimized media from Biohippo. Other preparations or formulations of media may result in suboptimal performance. Thaw Medium 1 (Biohippo #60187): MEM medium supplemented with 10% FBS, 1% non-essential amino acids, 1 mM Na pyruvate, 1% Penicillin/Streptomycin.Growth Medium 1C (Biohippo #79532): MEM medium supplemented with 10% FBS, 1% non-essential amino acids, 1 mM Na pyruvate, 1% Penicillin/Streptomycin plus 50 ug/ml of Hygromycin B
Host Cell	HEK293
Species	Cynomolgus Monkey
Synonyms	G-protein coupled receptor family C group 5 member D
Shipping Temperature	-80°C (dry ice)
Note	License Disclosure: Visit Biohippobioscience.com/license for the label license and other key information about this product. Troubleshooting Guide: Visit Biohippobioscience.com/cell-line-faq for detailed troubleshooting instructions. For all further questions, please email [email protected]. Warning: Avoid freeze/thaw cycles.

Storage Stability	Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHC18200116	78346	2 vials	$10340		Add to Cart

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