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GPRC5D (Cynomolgus) CHO Cell Line

SKU : BHC18200113

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BPS Bioscience

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Mfr.No.	78338
Description	Recombinant CHO-K1 cells stably expressing cynomolgus monkey (Macaca fascicularis) GPRC5D (accession #XP_005570250.1) under the control of a CMV promoter. Mycoplasma testing: The cell line has been screened to confirm the absence of Mycoplasma species. Host Species: hamster Supplied as Each vial contains 2 x 10⁶ cells in 1 ml of 10% DMSO
Background	The orphan G protein-coupled receptor, class C group 5 member D (GPRC5D) is a retinoic acid-inducible protein with seven transmembrane segments and a short N-terminal extracellular region. The strong and selective expression of GPRC5D in Multiple Myeloma cells, similar to the expression pattern of B-cell maturation antigen (BCMA), makes it a promising target for the treatment of Multiple Myeloma. It is anticipated that GPRC5D will be an alternative CAR T cell target for Multiple Myeloma immunotherapy.
Application	Cynomolgus GPRC5D binding assays; screen for cynomolgus GPRC5D ligands or antibodies.
Formulation	For best results, it is highly recommended to use these validated and optimized media from Biohippo. Other preparations or formulations of media may result in suboptimal performance. Thaw Medium 3 (Biohippo, #60186): Ham's F-12 medium supplemented with 10% FBS, 1% Penicillin/Streptomycin.Growth Medium 3B (Biohippo #79529): Ham's F-12 medium supplemented with 10% FBS, 1% Penicillin/Streptomycin plus 500 ug/ml of Hygromycin.
Host Cell	CHO
Species	Cynomolgus Monkey
Synonyms	G-protein coupled receptor family C group 5 member D
Shipping Temperature	-80°C (dry ice)
Note	License Disclosure: Visit Biohippobioscience.com/license for the label license and other key information about this product. Troubleshooting Guide: Visit Biohippobioscience.com/cell-line-faq for detailed troubleshooting instructions. For all further questions, please email [email protected]. Warning: Avoid freeze/thaw cycles.

Storage Stability	Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHC18200113	78338	2 vials	$10340		Add to Cart

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