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FAP- CHO K1 Recombinant Cell Line (High, Medium or Low Expression)-79947-M

SKU : BHC18200326

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Mfr.No.	79947-M
Description	Recombinant FAP-CHO K1 cell line stably expressing a full length human FAP-alpha protein (Genbank accession No: NM004460.2). Surface expression of FAP was confirmed by flow cytometry. Each stable clonal cell line was selected for different levels of FAP [removed]High, Medium, or Low) to mimic different stages of cancer target cells with various FAP expression levels. Mycoplasma testing: This cell line has been screened using the MycoAlert Mycoplasma Detection Kit (Lonza, #LT07-118) to confirm the absence of Mycoplasma contamination. MycoAlert Assay Control Set (Lonza, #LT07-518) was used as a positive control. Host Species: hamster Supplied as Each vial contains ~ 2 x 10^6 cells in 1 ml of 10% DMSO in FBS.
Background	Fibroblast activation protein alpha (FAP-alpha) belongs to the dipeptidyl peptidase IV (DPP4; CD26) gene family and is a cell-surface serine protease that acts on various hormones and extracellular matrix components. FAP expression under physiological conditions is scarce in healthy adult tissues. But FAP gene is highly upregulated in a wide variety of cancers, and is often used as a marker for pro-tumorigenic stroma. It has also been proposed as a molecular target of cancer therapies, and a great deal of research has gone into design and testing of diverse FAP-targeted treatments.
Application	Screen for activators or inhibitors of antibody-mediated signaling for immunotherapy research and drug discovery. Characterize FAP antibodies and ligands in binding assays.
Host Cell	CHO-K1
Species	Human
Synonyms	FAP-alpha cell line, Fibroblast activation protein alpha cell line, prolyl endopeptidase FAP cells, 79947-H, 79947-M, 79947-L
Shipping Temperature	-80°C (dry ice)
Note	License Disclosure: Purchase of this cell line grants you with a 10-year license to use this cell line in your immediate laboratory, for research use only. This license does not permit you to share, distribute, sell, sublicense, or otherwise make the cell line available for use to other laboratories, departments, research institutions, hospitals, universities, or biotech companies. The license does not permit use of this cell line in humans or for therapeutic or drug use. The license does not permit modification of the cell line in any way. Inappropriate use or distribution of this cell line will result in revocation of the license and result in an immediate cease of sales and distribution of Biohippo products to your laboratory. Biohippo does not warrant the suitability of the cell line for any particular use and does not accept any liability in connection with the handling or use of the cell line. Modifications of this cell line, transfer to another facility, or commercial use of the cells may require a separate license and additional fees; contact [email protected] for details. Publications using this cell line should reference Biohippo Inc. Warning: Avoid freeze/thaw cycles.

Storage Stability	Store in liquid nitrogen immediately upon receipt.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHC18200326	79947-M	2 vials	$8261		Add to Cart

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