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EpCAM CHO Cell Line

SKU : BHC18200168

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BPS Bioscience

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Mfr.No.	78683
Description	Recombinant clonal CHO cell line stably expressing full-length human EpCAM (NM_002354). Surface expression of EpCAM was confirmed by flow cytometry. The stable clonal cell line was selected for high levels of EpCAM expression compared to the parental CHO-K1 cell line. Mycoplasma testing: The cell line has been screened to confirm the absence of Mycoplasma species. Host Species: hamster Supplied as Each vial contains>1 x 10⁶ cells in 1 ml of Cell Freezing Medium (Biohippo #79796)
Background	Epithelial cell adhesion molecule (EpCAM, also known as CD90) is a known biomarker of epithelial cells that regulates cell proliferation and differentiation. It is used as an epithelial cell biomarker to detect circulating tumor cells. EpCAM belongs to the small GA₇₃₃ protein family and is a homophilic transmembrane glycoprotein involved in cell-cell adhesion and tissue plasticity. It is a single-chain membrane-spanning protein with three major domains known as EpEX, involved in epidermal growth factor receptor (EGFR) mediated signaling pathways. Due to the versatile function of EpCAM and its crosstalk with other signaling pathways in cancer, EpCAM is considered an attractive target for cancer diagnosis, prognosis, and potential therapies.
Application	Screen and validate antibodies against EpCAM for drug discovery and research Screen for compounds that regulate or inhibit EpCAM signaling in a cellular context Perform binding assays to screen for potential EpCAM ligands
Host Cell	CHO-K1 cells, Chinese Hamster Ovary, epithelial-like cells, adherent
Uniprot	P16422
Synonyms	EpCAM, CD326, Cell surface glycoprotein Trop-1
Shipping Temperature	-80°C (dry ice)
Note	License Disclosure: Visit Biohippobioscience.com/license for the label license and other key information about this product. Troubleshooting Guide: Visit Biohippobioscience.com/cell-line-faq for detailed troubleshooting instructions. For all further questions, please email [email protected]. Warning: Avoid freeze/thaw cycles

Storage Stability	Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage. Contact technical support at [email protected] if the cells are not frozen in dry ice upon arrival.

Reference	Liu, Y., et al. Exp Hematol Oncol 11: 97 (2022).

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHC18200168	78683	2 Vials	$7865		Add to Cart

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