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DAT - CHOK1 Recombinant Cell Line

SKU : BHC18200041

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BPS Bioscience

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Mfr.No.	60558
Description	Recombinant CHOK1 cell line expressing Human sodium-dependent dopamine transporter (DAT), Genbank accession number NM_001044 Mycoplasma testing: The cell line has been screened using the PCR-based VenorGeM Mycoplasma Detection kit (Sigma-Aldrich, #MP0025) to confirm the absence of Mycoplasma species. Host Species: hamster Supplied as Each vial contains ~2 X 10^6 cells in 1 ml of 10% DMSO
Background	The dopamine transporter (DAT, SLC6A3) is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synaptic cleft back into the cytosol, from which other transporters sequester DA and norepinephrine (NE) into vesicles for storage and later release. Dopamine reuptake via DAT provides the primary mechanism through which dopamine is cleared from synapses. DAT is implicated in a number of dopamine-related disorders, including attention deficit hyperactivity disorder, bipolar disorder, clinical depression, and alcoholism.
Application	Monitor dopamine uptake activity Screen for activators or inhibitors of DAT activities in a cellular context
Host Cell	CHO-K1
Synonyms	DAT, SLC6A3
Shipping Temperature	-80°C (dry ice)
Note	License Disclosure: Purchase of this cell line grants you with a 10-year license to use this cell line in your immediate laboratory, for research use only. This license does not permit you to share, distribute, sell, sublicense, or otherwise make the cell line available for use to other laboratories, departments, research institutions, hospitals, universities, or biotech companies. The license does not permit the use of this cell line in humans or for therapeutic or drug use. The license does not permit modification of the cell line in any way. Inappropriate use or distribution of this cell line will result in revocation of the license and result in an immediate cease of sales and distribution of Biohippo products to your laboratory. Biohippo does not warrant the suitability of the cell line for any particular use, and does not accept any liability in connection with the handling or use of the cell line. Modifications of this cell line, transfer to another facility, or commercial use of the cells may require a separate license and additional fees; contact [email protected] for details. Publications using this cell line should reference Biohippo Inc. Warning: Avoid freeze/thaw cycles.

Storage Stability	Immediately upon receipt, store in liquid nitrogen.

Reference	1. Vaughan, RA., et al., Trends in Pharmacological Sciences. 2013; 34(9): 489-496.2. Jorgensen, S., et al., Journal of Neuroscience methods. 2008; 169: 168-176.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHC18200041	60558	2 vials	$10340		Add to Cart

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