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CD14 CHO Recombinant Cell Line

SKU : BHC18200110

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BPS Bioscience

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Mfr.No.	78335
Description	Recombinant clonal CHO stable cell line constitutively expressing full length human CD14 protein. The surface expression of CD14 in this cell line was validated by flow cytometry. Mycoplasma testing: The cell line has been screened using the MycoAlert Mycoplasma Detection kit (Lonza, #LT07-218) to confirm the absence of Mycoplasma species. Host Species: hamster Supplied as Each vial contains 2 x 10⁶ cells in 1 ml of 10% DMSO in FBS
Background	CD14 (Cluster of Differentiation-14) is a surface antigen expressed predominantly by monocytes & macrophages. It is considered a patterned recognition receptor (PRR), which recognizes pathogen markers. Specifically, CD14 acts as a co-receptor for lipopolysaccharides (LPS) found in the outer membrane of gram-negative bacteria. Through this interaction, CD14 supports initiation of the innate immune response during bacterial infection. CD14 has also been found to contribute toward immune responses to viral pathogens such as human respiratory syncytial virus (RSV), and may amplify the inflammatory response observed in severe cases of SARS-CoV-2 infection (COVID-19). Monoclonal antibodies against CD14 are currently undergoing clinical trial as a candidate treatment to limit severe inflammatory responses common in patients hospitalized with COVID-19
Application	1. Useful for screening or performing binding assays of antibodies designed against human CD14 in a cellular context. 2. Cell-based assays for the assessment of CD14-mediated cell signaling and/or genetic responses under various experimental conditions (eg. inhibition/neutralization or activation/amplification).
Host Cell	CHO
Species	Human
Synonyms	Monocyte differentiation antigen CD14, CD_antigen CD14
Shipping Temperature	-80°C (dry ice)
Note	License Disclosure: Visit Biohippobioscience.com/license for the label license and other key information about this product. Troubleshooting Guide: Visit Biohippobioscience.com/cell-line-faq for detailed troubleshooting instructions. For all further questions, please email [email protected]. Warning: Avoid freeze/thaw cycles.

Storage Stability	Cells will arrive upon dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHC18200110	78335	2 vials	$7865		Add to Cart

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