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ADCC Bioassay Effector Cell (Mouse) - Jurkat Recombinant Cell Line

SKU : BHC18200208

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BPS Bioscience

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Mfr.No.	79733
Description	The mouse ADCC Reporter cells (mFcgammaRIV /NFAT-Jurkat cells) are recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of mouse FcgammaRIV (NM_144559.2). Mycoplasma testing: This cell line has been screened using the Venor GeM Mycoplasma Detection Kit, PCR Based (Sigma, #MP0025) to confirm the absence of Mycoplasma contamination. Host Species: human
Application	Characterize the Fc effector function of antibodies and measure ADCC activity in cellular assays.
Host Cell	Jurkat
Species	Mouse
Synonyms	Antibody-dependent cell-mediated cytotoxicity, natural killer bioassay, NK cell bioassay
Shipping Temperature	-80°C (dry ice)
Note	Warning: Avoid multiple freeze/thaw cycles.

Product Format	Two vials containing ~ 2 x 106 cells in 1 ml of 10% DMSO in FBS.
Storage Stability	Store in liquid nitrogen immediately upon receipt. Do not store for long-term at -80°C or on dry ice.

Reference	Bhavin S. Parekh, et al. 2012. "Development and validation of an antibody-dependent cellmediated cytotoxicity-reporter gene assay." mAbs, 4(3):310-318 , doi:10.4161/mabs.19873 Carlos Rosales. 2017. "FcgammaReceptor Heterogeneity in Leukocyte Functional Responses." Frontiers in Immunology, 8: 280, doi:10.3389/fimmu.2017.00280

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SKU	Supplier No.	Size	Your price	Quantity
BHC18200208	79733	2 vials	$6875		Add to Cart

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