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PMSA (FOLH1) - CHO Recombinant Cell Line (High, Medium, or Low Expression)

SKU : BHC18200314

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BPS Bioscience

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Mfr.No.	79641-H
Description	Recombinant clonal stable CHO cell line constitutively expressing full length human PMSA protein (Genbank #NM_004476.1). Surface expression of PMSA was confirmed by flow cytometry. Each stable clonal cell line was selected for different levels of PMSA expression to mimic different stages of cancer target cells with various PMSA expression levels. Mycoplasma testing: This cell line has been screened using the Quick Test Mycoplasma Detection Kit (Biotool.com, #B39032) to confirm the absence of Mycoplasma contamination. Host Species: hamster Supplied as Each vial contains ~ 2 x 10^6 cells in 1 ml of FBS + 10% DMSO.
Background	PMSA (prostate-specific membrane antigen), also known as Folate hydrolase 1 (FOLH1), is expressed at high levels on prostate cancer cells. It has been reported to play a role in tumor progression through the PI3K-Akt and MAPK-ERK1/2 pathways. PMSA/FOLH1 has been used as a target for imaging prostate cancer and is expressed in other tumor types and some normal tissues. Currently, PMSA/FOLH1 is the target of clinical trials of CAR-T cells and bi-specific antibodies.
Application	Useful for screening and validating antibodies against PMSA and PMSA CAR-T for immunotherapy research and drug discovery. Also useful for PMSA binding assays to screen for PMSA ligands.
Host Cell	CHO
Synonyms	FOLH1
Shipping Temperature	-80°C (dry ice)
Note	LICENSE DISCLOSURE: Purchase of this cell line grants you with a 10-year license to use this cell line in your immediate laboratory, for research use only. This license does not permit you to share, distribute, sell, sublicense, or otherwise make the cell line available for use to other laboratories, departments, research institutions, hospitals, universities, or biotech companies. The license does not permit the use of this cell line in humans or for therapeutic or drug use. The license does not permit modification of the cell line in any way. Inappropriate use or distribution of this cell line will result in revocation of the license and result in an immediate cease of sales and distribution of Biohippo products to your laboratory. Biohippo does not warrant the suitability of the cell line for any particular use, and does not accept any liability in connection with the handling or use of the cell line. Modifications of this cell line, transfer to another facility, or commercial use of the cells may require a separate license and additional fees; contact [email protected] for details. Publications using this cell line should reference Biohippo Inc. Warning: Avoid freeze/thaw cycles.

Storage Stability	Store in liquid nitrogen immediately upon receipt.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHC18200314	79641-H	2 vials	$7865		Add to Cart

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