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NET - CHOK1 Recombinant Cell Line

SKU : BHC18200040

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BPS Bioscience

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Mfr.No.	60557
Description	Recombinant CHOK1 cell line expressing human norepinephrine transporter (NET), Genbank accession number NM_001043. Mycoplasma testing: The cell line has been screened using the PCR-based VenorGeM Mycoplasma Detection kit (Sigma-Aldrich, #MP0025) to confirm the absence of Mycoplasma species. Host Species: hamster
Background	NET is a monoamine transporter responsible for the sodium-chloride (Na+/Cl¯)-dependent reuptake of extracellular norepinephrine (NE), also known as noradrenaline. NET can also reuptake extracellular dopamine (DA). The reuptake of these two neurotransmitters is essential in regulating concentrations in the synaptic cleft. NETs, along with the other monoamine transporters, play a key role in depression and neurodegenerative diseases (NDD) such as Alzheimer's and Parkinson's disease. NET is the target of many antidepressants and recreational drugs. In addition, an overabundance of NET is associated with ADHD.
Application	Monitor norepinephrine uptake activity and screen for activators or inhibitors of NET activities in a cellular context
Host Cell	CHO-K1
Shipping Temperature	-80°C (dry ice)
Note	FLIPR validation data is available upon request.License Disclosure:Purchase of this cell line grants you with a 10-year license to use this cell line in your immediate laboratory, for research use only. This license does not permit you to share, distribute, sell, sublicense, or otherwise make the cell line available for use to other laboratories, departments, research institutions, hospitals, universities, or biotech companies. The license does not permit use of this cell line in humans or for therapeutic or drug use. The license does not permit modification of the cell line in any way. Inappropriate use or distribution of this cell line will result in revocation of the license and result in an immediate cease of sales and distribution of Biohippo products to your laboratory. Biohippo does not warrant the suitability of the cell line for any particular use, and does not accept any liability in connection with the handling or use of the cell line. Modifications of this cell line, transfer to another facility, or commercial use of the cells may require a separate license and additional fees; contact [email protected] for details. Publications using this cell line should reference Biohippo Inc.

Product Format	Each vial contains ~2 X 10^6 cells in 1 ml of 10% DMSO
Storage Stability	Immediately upon receipt, store in liquid nitrogen.

Reference	1. Zhou, J., Drugs Future. 2004; 29(12): 1235-1244. 2. Jorgensen, S., et al., Journal of Neuroscience methods. 2008; 169: 168-176.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHC18200040	60557	2 vials	$10340		Add to Cart

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