The HVEM cell line is a recombinant clonal stable Jurkat T cell line expressing firefly luciferase gene under the control of 4 copies of NF-kB response elements with constitutive expression of human HVEM (Herpes Virus Entry Mediator, Tumor Necrosis Factor Receptor Superfamily Member 14, TNFRSF14, CD270, GenBank Accession No. NM_003820). Following activation by human HVEM ligand LIGHT, NF-B transcription factors bind to the DNA response elements to induce transcription of the luciferase reporter gene.
Categories
Transfected Stable Cell Lines
Application
For research use only
Host Cell
Jurkat T cell
Species
Human
Shipping
Dry Ice
Storage
Liquid Nitrogen
Reviews of HVEM/NF-kappaB Report Cell Line- Jurkat