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Home / Cells / Cell Lines

B2M Knockout THP-1 Cell Line

SKU : BHC18200128

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BPS Bioscience

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Mfr.No.	78389
Description	B2M (Beta-2-Microglobulin) has been genetically removed by CRISPR/Cas9 genome editing from THP-1 cells. Mycoplasma testing: The cell line has been screened to confirm the absence of Mycoplasma species. Host Species: human Supplied as Each vial contains 2 x 106 cells in 1 ml of cell freezing medium (Biohippo, #79796)
Background	THP-1 cells are monocytes, derived from an acute monocytic leukemia patient. Beta-2-Microglobulin is a required component of Major Histocompatibility Complex (MHC) class 1 molecules, which present peptide fragments from within the cell to cytotoxic T cells as part of the adaptive immune system. B2M plays an essential role both in governing MHC class I molecule stability and in promoting antigen binding and presenting the antigen to CD3/TCR complex of CD8+ T cells.
Application	Study the consequences of B2M knock-down Study T cell activation, antigen presentation, and immune responses
Host Cell	THP-1, monocyte, suspension
Uniprot	P61769
Synonyms	B2M, Beta-2-microglobulin, Beta-2-microglobulin form pI 5.3, CDABP0092, HDCMA22P
Shipping Temperature	-80°C (dry ice)
Note	License Disclosure: Visit Biohippobioscience.com/license for the label license and other key information about this product. Troubleshooting Guide: Visit Biohippobioscience.com/lentivirus-faq for detailed troubleshooting instructions. For all further questions, please email [email protected] Warning: Avoid freeze/thaw cycles.

Storage Stability	Cells are shipped in dry ice and should immediately be thawed or stored in liquid nitrogen upon receipt. Do not use a -80°C freezer for long term storage.

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHC18200128	78389	2 vials	$7150		Add to Cart

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