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Home / Primary Antibodies / Monoclonal Antibodies

CDK2

SKU : BHA15100332

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BioGenex Laboratories

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Mfr.No.	AN906-5M
Clonality	Monoclonal
Description	CDK2 (Cyclin-dependent kinase 2), also known as cell division protein kinase 2, is a serine/threonine protein kinases that participate in cell cycle regulation and is especially critical during the G1 to S phase transition. CDK2 phosphorylates a large number of proteins involved in cell cycle progression (e.g. p27KIP1 and RB), DNA replication (e.g., replication factors A and C), histone synthesis (e.g., NPAT), centrosome duplication (e.g., nucleophosmin), among other processes. CDK2 is known to phosphorylate Akt on Ser477 and Thr479 promoting its activation at a specific stage during cell cycle progression . Recently, it has become clear that deregulation of CDK2 also occurs frequently in certain types of cancer. Increased CDK2 activity was shown to decreases risk in colon cancer, but elevates poor outcome in specific tumors, including low grade glioma, kidney, thyroid, adrenocortical and prostate cancer.
Host	Rabbit
Isotype	IgG
Reactivity	Human
Species	Rabbit

Clone No	SP80
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:20-50

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
AN906-5M	AN906-5M	6 mL	$356		Add to Cart
AN906-10M	AN906-10M	100 tests - i6000	$667		Add to Cart
AY906-50D	AY906-50D	50 tests - Xmatrx	$373		Add to Cart
AY906-YCD	AY906-YCD	160 tests - Xmatrx	$909		Add to Cart
NU906-UC	NU906-UC	1ml Conc	$727		Add to Cart
NU906-5UC	NU906-5UC	0.5ml Conc	$509		Add to Cart

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