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Home / Primary Antibodies / Monoclonal Antibodies

CD73

SKU : BHA15100330

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BioGenex Laboratories

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Mfr.No.	AM904-5M
Clonality	Monoclonal
Description	CD73 or NT5E (ecto-5-nucleotidase) is a GPI-anchored enzyme that generates extracellular adenosine, a potent immunosuppressive metabolite in the tumor microenvironment. CD73adenosinergic pathway contributes to tumor immune escape in animal mouse models of cancerand was also shown to suppress antitumor T cells in human ovarian cancer. Monoclonal antibody treatment targeting CD73 has been shown to delay ovarian tumor growth in mice and to rescue human T-cell functions when co-cultured with CD73-expressing human ovarian cancer cells. CD73 over expression was demonstrated in various cancer including breast cancer, colon cancer, glioma, leukemia, melanoma, ovarian cancer, pancreatic cancer, prostate cancer and thyroid cancer.
Host	Mouse
Isotype	IgG
Reactivity	Human
Species	Mouse

Clone No	1D7
Research Area	Infectious diseases, Immune system

Buffer	PBS
Concentration	1-3ug/ml
Storage	2-8°C

Applications	IHC
Dilution	1:50-100

Product Manual	Datasheet SDS

No Description Available.

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Combination SKU	Supplier No.	Size	Your price	Quantity
AM904-5M	AM904-5M	6 mL	$339		Add to Cart
AM904-10M	AM904-10M	100 tests - i6000	$633		Add to Cart
AX904-50D	AX904-50D	50 tests - Xmatrx	$356		Add to Cart
AX904-YCD	AX904-YCD	160 tests - Xmatrx	$866		Add to Cart
MU904-UC	MU904-UC	1ml Conc	$696		Add to Cart
MU904-5UC	MU904-5UC	0.5ml Conc	$489		Add to Cart

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