CD20 is a 33-37 kDa transmembrane phosphoprotein. CD20 is a B-lymphocyte surface molecule that is widely expressed during B-cell ontogeny, from early pre-B-cell developmental stages until final differentiation into plasma cells. CD20 functions as calcium-permeable cation channel. It is involved in the regulation of B-cell activation and proliferation. CD20 serves as a useful target for antibody-mediated therapeutic depletion of B-cells.
Categories
Primary Antibodies
Clonality
polyclonal
Host
Rabbit
Immunogen
membrane-spanning 4-domains, subfamily A, member 1
Isotype
IgG
Molecular Weight
33 kDa
Reactivity
Human
Regulatory
RUO
Synonyms
B lymphocyte antigen CD20, B1, Bp35, CD20, LEU 16, MS4A1, MS4A2, S7
Uniprot
P11836
Research Area
Stem Cells, Immunology, Signal Transduction, Cancer
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)