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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hCD3EDG/hEpCAM
- Strain : Repository Live
- KI/KO Gene : CD3E
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Cd3
- Description : hCD3EDG(NM-HU-2
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hCD47(Balb/c,2)
- Strain : Embryo cryopres
- KI/KO Gene : CD47
- Research Application : Immunotherapy
- Nomenclature : BALB/cAnSmoc-Cd
- Description : The endogenous
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hTNFSF11/hSIGLEC15
- Strain : Embryo cryopres
- KI/KO Gene : SIRPA
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Tnf
- Description : hTNFSF11(NM-HU-
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Rag2/IL2rg-KO/hCD40
- Strain : Developing
- KI/KO Gene : CD40
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Cd4
- Description : The Rag2 and Il
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hIL2/hIL2RB/hIL2RG
- Strain : Repository Live
- KI/KO Gene : IL2
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Il2
- Description : hIL2RG(NM-HU-20
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hIL2/hIL2RA
- Strain : Repository Live
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Il2
- Description : hIL2(NM-HU-1900
- Synonyms : Il-2,I, CD25, I
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hIL2RA/hIL2RB/hIL2RG
- Strain : Repository Live
- KI/KO Gene : IL2RA
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Il2
- Description : hIL2RA(NM-HU-19
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hIL3/hCSF2/hSIRPA(2)/hCD47
- Strain : Repository Live
- KI/KO Gene : IL3
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Il3
- Description : hIL3(NM-HU-1900
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hIL4/hIL4R
- Strain : Repository Live
- KI/KO Gene : IL4
- Research Application : Immunotherapy
- Nomenclature : C57BL/6Smoc-Il4
- Description : These mice are
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hIL7(BALB/c)
- Strain : Repository Live
- KI/KO Gene : Il7r
- Research Application : Humanized Drug
- Nomenclature : BALB/cAnSmoc-Il
- Description : The endogenous
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hLILRB2-hLILRB3-Tg
- Strain : Repository Live
- KI/KO Gene : LILRB2
- Research Application : Humanized Drug
- Nomenclature : C57BL/6Smoc-Tg(
- Description : These transgeni
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