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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hTIGIT(BALB/c,2)
- Nomenclature : BALB/cAnSmoc-Ti
- KI/KO Gene : Tigit
- Strain : Developing
- Target : Immune Checkpoi
- Description : Model Descripti
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hTNFSF11/hSIGLEC15
- Nomenclature : C57BL/6JSmoc-Tn
- KI/KO Gene : TNFSF11
- Research Application : Immunotherapy
- Strain : Developing
- Target : Cytokines
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hTNFRSF1B/hIL2RA
- Nomenclature : C57BL/6JSmoc-Tn
- KI/KO Gene : TNFRSF1B
- Research Application : Immunotherapy
- Strain : Embryo cryopres
- Description : Model Descripti
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pCdh16-hENPP3-Tg
- Nomenclature : C57BL/6JSmoc-Tg
- Strain : Developing
- Target : Tumor Targets
- Description : Model Descripti
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pAlb-hAPOB-Tg
- Nomenclature : C57BL/6JSmoc-Tg
- KI/KO Gene : APOB
- Strain : Repository Live
- Target : Metabolic Targe
- Description : Model Descripti
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Ighm/Ighd-KO/hSIRPA/hCD47
- Nomenclature : C57BL/6JSmoc-Ig
- KI/KO Gene : SIRPA
- Strain : Developing
- Description : Model Descripti
- Synonyms : Bit, P84, SIR
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Rag2/IL2rg-KO/hCD40
- Nomenclature : C57BL/6JSmoc-Cd
- KI/KO Gene : CD40
- Research Application : Immunotherapy
- Strain : Developing
- Target : Immune Checkpoi
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hCLDN18.2-Tg
- Nomenclature : C57BL/6JSmoc-Tg
- Strain : Developing
- Target : Tumor Targets
- Description : Model Descripti
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hENTPD1(2)
- Nomenclature : C57BL/6JSmoc-En
- KI/KO Gene : Entpd1
- Research Application : Tumor research
- Strain : Embryo cryopres
- Description : Model Descripti
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hANGPTL3(5)
- Nomenclature : C57BL/6JSmoc-An
- KI/KO Gene : Angptl3
- Strain : Developing
- Description : Model Descripti
- Synonyms : hypl
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