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Humanized Knockins
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Humanized Knockins
The humanized knockin mouse model is a general term that refers to a mouse that has been engrafted with a short strand of human DNA. These strains may be used to streamline drug development, assess PK/PD of novel therapeutics, model human disease and explore pathogenic mechanisms, and more.
775 Result Found
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hCD3E/hSDC1
- Description : hCD3E(NM-HU-001
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Repository Live
- KI/KO Gene : CD3E
- Synonyms : CD3; T3e; AI5
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hCD3E/hCD20(2)
- Description : hCD3E(NM-HU-001
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Embryo cryopres
- KI/KO Gene : CD3E
- Synonyms : CD3; T3e; AI5
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hCD3EDG/hCD28/hCD38(2)
- Description : hCD3EDG/hCD28(N
- Nomenclature : C57BL/6Smoc-Cd3
- Strain : Repository Live
- KI/KO Gene : CD28
- Synonyms : CD3 T3e AI50478
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hCD3EDG(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/c-Cd3etm1(
- Strain : Repository Live
- KI/KO Gene : CD3E
- Synonyms : CD3; T3e; AI5
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hCD40L(BALB/c)
- Description : The endogenous
- Nomenclature : BALB/cAnSmoc-Cd
- Strain : Embryo cryopres
- KI/KO Gene : Cd40lg
- Synonyms : IGM, IMD3, Ly62
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hCD81/hOCLN
- Description : These mice are
- Nomenclature : C57BL/6Smoc-Cd8
- Strain : Embryo cryopres
- KI/KO Gene : CD81
- Synonyms : Tapa1; Tapa-1;
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hCSF1(NMG)
- Description : The endogenous
- Nomenclature : NOD-PrkdcscidIl
- Strain : Developing
- KI/KO Gene : Csf1
- Synonyms : op,Csfm,MCSF,C8
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hCTLA-4/Cd8a-IRES-Luc-2A-EGFP
- Description : hCTLA4(NM-HU-00
- Nomenclature : C57BL/6Smoc-Ctl
- Strain : Embryo cryopres
- KI/KO Gene : Cd8a
- Synonyms : Ly-2; Ly-B; L
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Rag2-KO/hVEGFR2
- Description : The Rag2 gene o
- Nomenclature : C57BL/6Smoc-Kdr
- Strain : Embryo cryopres
- KI/KO Gene : Rag2
- Synonyms : Rag-2
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Rag2/IL2rg-KO/hVEGFR2
- Description : IL2rg-KO (NM-KO
- Nomenclature : C57BL/6Smoc-Il2
- Strain : Repository Live
- KI/KO Gene : IL2RG
- Synonyms : gc; p64; (g)c
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