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Home / Primary Antibodies / Polyclonal Antibodies

Caspase 8 antibody

SKU : BHA10810012

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Mfr.No.	FNab10024
Background	Caspase 8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3(PMID:21816816). It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. This antibodycan recognize pro-and cleaved-caspase 8.
Clonality	polyclonal
Host	Rabbit
Immunogen	caspase 8, apoptosis-related cysteine peptidase
Immunogen Region	caspase 8, apoptosis-related cysteine peptidase
Isotype	IgG
Molecular Weight	53-57 kDa, 32-45 kDa
Reactivity	Human, Mouse
Recommended Dilution	WB: 1:500-1:2000; IHC: 1:50-1:500
Synonyms	Apoptotic cysteine protease, Apoptotic protease Mch 5, Casp 8, CASP8, Caspase 8, Caspase 8/p18, Caspase8, FADD like ICE, FLICE, ICE like apoptotic protease 5, MACH, MCH5

Uniprot	Q14790
Gene Id	841
Research Area	cancer, Signal Transduction, Metabolism

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:500-1:2000; IHC: 1:50-1:500

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10024.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810012	FNab10024	100ug	$260		Add to Cart

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