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Home / Primary Antibodies / Polyclonal Antibodies

Caspase 1 antibody

SKU : BHA10810003

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Mfr.No.	FNab10015
Background	CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta(IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products(PMID:21804020). It has 5 isoforms produced by alternative splicing.
Clonality	polyclonal
Host	Rabbit
Immunogen	caspase 1
Immunogen Region	caspase 1
Isotype	IgG
Molecular Weight	45-47 kDa, 30 kDa, 35 kDa
Reactivity	Human, Mouse
Recommended Dilution	WB: 1:200-1:2000; IHC: 1:50-1:500
Synonyms	CASP 1, CASP1, Caspase 1, Caspase 1/p20/p10, Caspase1, ICE, IL 1 beta converting enzyme, IL 1BC, IL1BC, IL1BCE, Interleukin 1 beta convertase, p10, p20, P45

Uniprot	P29466
Gene Id	834
Research Area	Signal Transduction, Metabolism, Cardiovascular, Neuroscience

Form	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Tested Application	WB: 1:200-1:2000; IHC: 1:50-1:500

Product Manual	<a href="https://www.fn-test.com/content/uploads/product/manuals/antibody/FNab10015.pdf" target="_blank">Data Sheet</ a>

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SKU	Supplier No.	Size	Your price	Quantity
BHA10810003	FNab10015	100ug	$260		Add to Cart

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