Xevinapant

Mfr.No.	T6763
Description	Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide. Phase 1.
Alternative Names	AT406
Molecular Formula	C32H43N5O4
Signaling Pathways	Apoptosis
Smiles	C(NC(C1=CC=CC=C1)C2=CC=CC=C2)(=O)(CH)3N4(C)(CC3)(CCN(C(CC(C)C)=O)C(CH)(NC((CH)(NC)C)=O)C4=O)(H)
Cas Number	1071992-99-8
Molecular Weight	561.71
Target	IAP

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SKU	Supplier No.	Size	Your price
BHB20434908	T6763	1 mL	$148	Add to Cart
BHB20434908	T6763	1 mg	$36	Add to Cart
BHB20434908	T6763	2 mg	$52	Add to Cart
BHB20434908	T6763	5 mg	$85	Add to Cart
BHB20434908	T6763	10 mg	$133	Add to Cart
BHB20434908	T6763	25 mg	$293	Add to Cart
BHB20434908	T6763	50 mg	$553	Add to Cart
BHB20434908	T6763	100 mg	$785	Add to Cart
BHB20434908	T6763	200 mg	$1060	Add to Cart
BHB20434908	T6763	500 mg	$1390	Add to Cart