WYE-354

Mfr.No.	T6731
Description	WYE-354(IC50=5 nM) is an effective, selective and ATP-competitive mTOR inhibitor. It blocks mTORC2/P-AKT(S473) and mTORC1/P-S6K(T389), not P-AKT(T308). The selectivity for mTOR is higher than PI3Kalpha (>100-fold) and PI3Kgamma (>500-fold).
Alternative Names	WYE354
Molecular Formula	C24H29N7O5
Signaling Pathways	Apoptosis, PI3K/Akt/mTOR signaling, Autophagy
Smiles	C(OC)(=O)N1CCC(N2C=3C(=C(N=C(N3)C4=CC=C(NC(OC)=O)C=C4)N5CCOCC5)C=N2)CC1
Cas Number	1062169-56-5
Molecular Weight	495.53
Target	Autophagy, mTOR, PI3K, Apoptosis

Have you used this product?

SKU	Supplier No.	Size	Your price
BHB20434877	T6731	1 mL	$47	Add to Cart
BHB20434877	T6731	5 mg	$43	Add to Cart
BHB20434877	T6731	10 mg	$77	Add to Cart
BHB20434877	T6731	25 mg	$158	Add to Cart
BHB20434877	T6731	50 mg	$296	Add to Cart
BHB20434877	T6731	100 mg	$383	Add to Cart