Tuvusertib

Mfr.No.	T10406
Description	Tuvusertib (M1774) is an orally available ataxia telangiectasia and Rad3-related (ATR) kinase inhibitor (Ki< 1 uu) with selective and potentially antitumor activity.Tuvusertib selectively inhibits ATR activity and blocks downstream phosphorylation of serine/threonine protein kinase checkpoint kinase 1 (CHK1), thereby inhibits DNA damage checkpoint activation, disrupting DNA damage repair and inducing apoptosis in tumor cells.
Alternative Names	ATR inhibitor 1
Molecular Formula	C16H12F2N8O
Signaling Pathways	DNA Damage/DNA Repair, Apoptosis, PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint, Others
Smiles	C(NC=1C(=C(F)C=NC1)C2=CN=CN2C)(=O)C3=C4N(N=C3N)C=C(F)C=N4
Cas Number	1613200-51-3
Molecular Weight	370.32
Target	Others, ATM/ATR, Apoptosis, Chk

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SKU	Supplier No.	Size	Your price
BHB20401124	T10406	1 mL	$187	Add to Cart
BHB20401124	T10406	1 mg	$68	Add to Cart
BHB20401124	T10406	5 mg	$165	Add to Cart
BHB20401124	T10406	10 mg	$257	Add to Cart
BHB20401124	T10406	25 mg	$496	Add to Cart
BHB20401124	T10406	50 mg	$692	Add to Cart
BHB20401124	T10406	100 mg	$979	Add to Cart