Triacsin C

Mfr.No.	SIH-203
Alternative Names	(3E)-1-Oxo-3-[(2E,4E,7E)-2,4,7-undecatrien-1-ylidene]triazane
Appearance	Oil dissolved in DMSO (1mg/ml)
Function	Acyl-CoA synthetase inhibitor
Inchi	InChI=1S/C11H17N3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15/h4-5,7-11H,2-3,6H2,1H3,(H,13,15)/b5-4+,8-7+,10-9+,12-11+
Inchikey	NKTGCVUIESDXPU-YLEPRARLSA-N
Mode Of Action	Inhibitor
Molecular Formula	C11H17N3O
Pubchem Cid	9576787
Published Application	In vitro inhibition
Published Species Reactivity	Human
Pubmed Id	26016511
Research Area	Cancer ; Apoptosis
Safety Phrases	Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Smiles	CCC/C=C/C/C=C/C=C/C=N/NN=O
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Cas Number	76896-80-5
Molecular Weight	207.27
Scientific Background	Triacsin C is a potent inhibitor of long fatty acyl CoA synthetase. It blocks beta-cell apoptosis. It also blocks the de novo synthesis of triglyercides, diglycerides and cholesterol esters, interfering with lipid metabolism (1). It is also a potent vasodilator.
Solubility	Soluble in DMSO (25 mg/ml) or methanol (5 mg/ml)
Source	Synthetic
Adr Code	Non-hazardous
Country Of Origin	Canada
Tarriff Code	3822.00.1090

Reference	1. Igal R.A., Wang P., Coleman R.A. (1997) Biochem J. 324(Pt2): 529-534.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB11900032-2	SIH-203-1MG	1 mg	$502		Add to Cart
BHB11900032-1	SIH-203-100UG	100 ug	$111		Add to Cart