TG003

Mfr.No.	SIH-515
Alternative Names	TG 003, (1Z)-1-(3-Ethyl-5-methoxy-2(3H)-benzothiazolylidene)-2-propanone
Appearance	Yellow solid
Function	Clk family kinase inhibitor
Inchi	InChI=1S/C13H15NO2S/c1-4-14-11-8-10(16-3)5-6-12(11)17-13(14)7-9(2)15/h5-8H,4H2,1-3H3/b13-7-
Inchikey	BGVLELSCIHASRV-QPEQYQDCSA-N
Mode Of Action	Inhibitor
Molecular Formula	C13H15NO2S
Pubchem Cid	1893668
Research Area	Cell Signaling ; Cancer ; Apoptosis ; Cancer Growth Inhibitors ; Tyrosine Kinase Inhibitors
Safety Phrases	Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Smiles	CCN1C2=C(C=CC(=C2)OC)S/C1=CC(=O)C
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Cas Number	719277-26-6
Molecular Weight	249.3
Scientific Background	TG003 is a potent inhibitor of the CDC-like (Clk) family kinases. It has been shown to suppress serine/arginine-rich protein phosphorylation.
Solubility	Soluble to 100 mM in DMSO and to 75 mM in ethanol
Source	Synthetic
Adr Code	Non-hazardous
Country Of Origin	Canada
Tarriff Code	3822.00.1090

Reference	1. Muraki M., et al. (2004) J. Biol. Chem. 279(23): 24246–24254.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB11900298-1	SIH-515-5MG	5 mg	$101		Add to Cart
BHB11900298-2	SIH-515-25MG	25 mg	$404		Add to Cart