SRPIN340

Mfr.No.	SIH-514
Alternative Names	N-[2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide ;
Appearance	Off-white solid
Function	SR kinase inhibitor
Inchi	InChI=1S/C18H18F3N3O/c19-18(20,21)14-4-5-16(24-10-2-1-3-11-24)15(12-14)23-17(25)13-6-8-22-9-7-13/h4-9,12H,1-3,10-11H2,(H,23,25)
Inchikey	DWFGGOFPIISJIT-UHFFFAOYSA-N
Mode Of Action	Inhibitor
Molecular Formula	C18H18F3N3O
Pubchem Cid	2797577
Research Area	Cell Signaling ; Cancer ; Apoptosis ; Cancer Growth Inhibitors ; Tyrosine Kinase Inhibitors
Safety Phrases	Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Smiles	C1CCN(CC1)C2=C(C=C(C=C2)C(F)(F)F)NC(=O)C3=CC=NC=C3
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Cas Number	218156-96-8
Molecular Weight	349.4
Scientific Background	SRPIN340 is a selective inhibitor of serine–arginine protein kinases (SRPK). It has been shown to inhibit SRPK1, as well as, SRPK2, at higher concentrations. SRPIN340 is ATP-competitive.
Solubility	Soluble to 100 mM in DMSO and to 50 mM in 1eq. HCl
Source	Synthetic
Adr Code	Non-hazardous
Country Of Origin	Canada
Tarriff Code	3822.00.1090

Reference	1. Karakama Y., et al. (2010). Antimicrobial Agents Chemo. 54(8): 3179–3186.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB11900297-1	SIH-514-5MG	5 mg	$85		Add to Cart
BHB11900297-2	SIH-514-25MG	25 mg	$337		Add to Cart