SGK1 inhibitor

Mfr.No.	T71947
Description	SGK1 inhibitor is an inhibitor of serum- and glucocorticoid-regulated kinase 1 (SGK1) and SGK2. It is selective for SGK1 and SGK2 over SGK3 in the presence of a high concentration of ATP. SGK1 inhibitor prevents phosphorylation of GSK3beta in U2OS cells and decreases cell viability in BYL719-insensitive HCC1954 cells when used in combination with the PI3Kalpha inhibitor BYL719. SGK1 inhibitor reduces tumor growth in an HCC1954 mouse xenograft model when administered in combination with BYL719.
Molecular Formula	C17H12Cl2N6O2S
Signaling Pathways	Others
Smiles	N(S(=O)(=O)C1=C(Cl)C(Cl)=CC=C1)C2=CC=C(C=3N=C4C(=NC3)C(N)=NN4)C=C2
Cas Number	1426214-51-8
Molecular Weight	435.29
Target	Others

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SKU	Supplier No.	Size	Your price
BHB20439223	T71947	1 mg	$93	Add to Cart
BHB20439223	T71947	5 mg	$423	Add to Cart
BHB20439223	T71947	10 mg	$798	Add to Cart
BHB20439223	T71947	25 mg	$1760	Add to Cart