SC 79

Mfr.No.	SIH-512
Alternative Names	SC-79, SC79, 2-Amino-6-chloro-α-cyano-3-(ethoxycarbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester
Appearance	White solid
Function	Akt kinase activator
Mode Of Action	Activator
Molecular Formula	C17H17ClN2O5
Research Area	Cell Signaling
Safety Phrases	Classification: Not a hazardous substance or mixture. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Smiles	CCOC(=O)C1=C(OC2=C(C1C(C#N)C(=O)OCC)C=C(C=C2)Cl)N
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Cas Number	305834-79-1
Molecular Weight	364.8
Scientific Background	SC 79 is an activator of Akt (protein kinase B). Specifically, it has been shown to bind the plecktrin homology (PH) domain of Akt. This mimics the binding of Phosphatidylinositol (3,4,5)-trisphosphates, which induces a conformational change in Akt, that enhances phosphorylation and activation.
Solubility	May be dissolved in DMSO (100mg/mL); or ethanol (40mg/mL, warm)
Source	Synthetic
Adr Code	Non-hazardous
Country Of Origin	Canada
Tarriff Code	3822.00.1090

Reference	1. Jo H., et al. (2012) Pro. Nat. Acad. Sci. USA. 109(26): 10581–10586.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB11900295-1	SIH-512-5MG	5 mg	$90		Add to Cart
BHB11900295-2	SIH-512-25MG	25 mg	$359		Add to Cart