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PF-5274857 mseylate (1373615-35-0 free base)

SKU : BHB20418233

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Description
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Mfr.No.	T28388
Description	PF-5274857 is a potent, orally active and selective inhibitor of hedgehog (Hh) signaling pathway (IC50 = 5.8 nM, Ki = 4.6 nM) . PF-5274857 effectively penetrates the blood-brain barrier and inhibits Smo activity in the brain of primary medulloblastoma mice, resulting in improved animal survival rates.
Alternative Names	PF-5274857
Molecular Formula	C21H29ClN4O6S2
Signaling Pathways	Others
Smiles	O=C(N1CCN(C2=NC=C(Cl)C(C3=NC=C(C)C=C3C)=C2)CC1)CCS(=O)(C)=O.OS(=O)(C)=O
Molecular Weight	533.06
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20418233	T28388	100 mg	-		Add to Quote
BHB20418233	T28388	500 mg	-		Add to Quote

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PF-5274857 mseylate (1373615-35-0 free base)

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