MTK458

Mfr.No.	T72420
Description	MTK458 (EP-0035985) is an orally active and brain-permeable PINK1 activator that promotes pathological clearance of alpha-synuclein and reduces pUb in a PFF inoculation model.MTK458 induces pathological alpha-synuclein clearance by stimulating dimerization and stabilization of the PINK1/TOM complex.MTK458 may be used in Parkinson's disease research.
Alternative Names	EP-0035985
Molecular Formula	C17H15F3N4
Signaling Pathways	PI3K/Akt/mTOR signaling
Smiles	N(C1=C2C(NC(C(F)(F)F)=C2)=NC=N1)(CH)3C=4C(CCC3)=CC=CC4
Cas Number	2499962-58-0
Molecular Weight	332.32
Target	PTEN

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SKU	Supplier No.	Size	Your price
BHB20439591	T72420	1 mL	$253	Add to Cart
BHB20439591	T72420	1 mg	$93	Add to Cart
BHB20439591	T72420	5 mg	$228	Add to Cart
BHB20439591	T72420	10 mg	$363	Add to Cart
BHB20439591	T72420	25 mg	$745	Add to Cart
BHB20439591	T72420	50 mg	$1180	Add to Cart
BHB20439591	T72420	100 mg	$1620	Add to Cart