Miransertib (ARQ 092) HCl

Mfr.No.	T22247
Description	Miransertib hydrochloride (ARQ-092 hydrochloride) is a powerful, orally bioavailable, selective, and allosteric inhibitor of Akt. It exhibits an inhibitory concentration (IC50) of 2.7 nM, 14 nM, and 8.1 nM against Akt1, Akt2, and Akt3, respectively. In addition to its Akt inhibitory activity, Miransertib hydrochloride also demonstrates significant potency as an inhibitor of the AKT1-E17K mutant protein. This compound shows promise in research related to PI3K/AKT-driven tumors and Proteus syndrome. Furthermore, Miransertib hydrochloride displays efficacy against Leishmania (1, 2).
Molecular Formula	C27H25ClN6
Signaling Pathways	Others
Smiles	Cl.N=1C=CC=C(C1N)C2=NC=3C=CC(=NC3N2C4=CC=C(C=C4)C5(N)CCC5)C=6C=CC=CC6
Cas Number	1313883-00-9
Molecular Weight	468.98
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20412095	T22247	2 mg	$59		Add to Cart