LY 294002

Mfr.No.	SIH-252
Alternative Names	2-(4-Morpholinyl)-8-phenyl-4H-chromen-4-one
Appearance	White Crystalline Solid
Function	PI 3-Kinase inhibitor
Inchi	InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2
Inchikey	CZQHHVNHHHRRDU-UHFFFAOYSA-N
Mode Of Action	Inhibitor
Molecular Formula	C19H17NO3•HCl
Pubchem Cid	3973
Published Application	In vitro inhibition
Published Species Reactivity	Human
Pubmed Id	25616727
Research Area	Cancer ; Apoptosis ; Cancer Growth Inhibitors ; Tyrosine Kinase Inhibitors
Safety Phrases	Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
Smiles	C1COCCN1C2=CC(=O)C3=C(O2)C(=CC=C3)C4=CC=CC=C4
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Cas Number	154447-36-6
Molecular Weight	343.81
Scientific Background	LY294002 is a potent inhibitor of PI3Ks. It inhibits proliferation and induces apoptosis in human colon cancer cells in vitro and in vivo (1).
Solubility	Soluble to 5 mM in ethanol and to 25 mM in DMSO
Source	Synthetic
Adr Code	Non-hazardous
Country Of Origin	Canada
Tarriff Code	3822.00.1090

Reference	1. Vlahos, et al. (1994) J Biol Chem. 269: 5241.

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHB11900074-1	SIH-252-5MG	5 mg	$95		Add to Cart
BHB11900074-2	SIH-252-25MG	25 mg	$381		Add to Cart