KW-2450 free base

Mfr.No.	T68405
Description	KW-2450 free base is an orally bioavailable inhibitor of insulin-like growth factor 1 receptor (IGF-1R) and insulin receptor (IR) tyrosine kinases with potential antineoplastic activity. IGF-1R/IR inhibitor KW-2450 free base selectively binds to and inhibits the activities of IGF-1R and IR, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. IGF-R1 and IR tyrosine kinases, overexpressed in a variety of human cancers, play significant roles in the stimulation of cellular proliferation, oncogenic transformation, and suppression of apoptosis.
Molecular Formula	C28H29N5O3S
Signaling Pathways	Tyrosine Kinase/Adaptors
Smiles	C(=C/C1=C(NC(=O)C=2SC=CC2C)C=C(CN3CCN(C(CO)=O)CC3)C=C1)C=4C=5C(NN4)=CC=CC5
Cas Number	904899-25-8
Molecular Weight	515.63
Target	IGF-1R

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SKU	Supplier No.	Size	Your price
BHB20435595	T68405	1 mg	$588	Add to Cart
BHB20435595	T68405	2 mg	$843	Add to Cart
BHB20435595	T68405	5 mg	$1280	Add to Cart
BHB20435595	T68405	10 mg	$1730	Add to Cart
BHB20435595	T68405	25 mg	$2570	Add to Cart
BHB20435595	T68405	50 mg	$3380	Add to Cart