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JNJ-1013

SKU : BHB20442657

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Description
Review(s)

Mfr.No.	T78054
Description	JNJ-1013 is a potent and selective IRAK1 degrader, demonstrating IC50 values of 72 nM for IRAK1, 443 nM for IRAK4, and 1071 nM for VHL FP. It induces apoptosis and augments the expression of cleaved PARP while decreasing the expression of IRAK1, p-IKBalpha, and pSTAT3(Tyr705) (1).
Molecular Formula	C46H55N9O7S
Signaling Pathways	Apoptosis
Smiles	C((CH)(NC(COC1CCN(CC1)C2=CC(OC)=C(NC(=O)C=3N=C(C=CC3)C=4C=CNN4)C=C2)=O)C(C)(C)C)(=O)N5(CH)(C(N(CH)(C)C6=CC=C(C=C6)C=7SC=NC7C)=O)C(CH)(O)C5
Cas Number	2597343-08-1
Molecular Weight	878.05
Target	Apoptosis

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SKU	Supplier No.	Size	Your price	Quantity
BHB20442657	T78054	5 mg	$673		Add to Cart

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JNJ-1013

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