Isradipine

Mfr.No.	SIH-314
Alternative Names	Isopropyl methyl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate, PN 200-110
Appearance	Yellow Crystalline Solid
Function	L-type Ca channel blocker
Inchi	InChI=1S/C19H21N3O5/c1-9(2)26-19(24)15-11(4)20-10(3)14(18(23)25-5)16(15)12-7-6-8-13-17(12)22-27-21-13/h6-9,16,20H,1-5H3
Inchikey	HMJIYCCIJYRONP-UHFFFAOYSA-N
Mode Of Action	Inhibitor
Molecular Formula	C19H21N3O5
Pubchem Cid	3784
Research Area	Neuroscience ; Ion Channels ; Calcium Channels ; Voltage-Gated Calcium Channels
Safety Phrases	Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302-H315-H317-H318-H335 Precautionary Phrases: P261-P280-P305 + P351 + P338
Smiles	CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC=CC3=NON=C32)C(=O)OC
Field Of Use	Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
Cas Number	75695-93-1
Molecular Weight	371.39
Scientific Background	Isradipine is a calcium channel blocker of the dihydropyridine class. It is usually used in the treatment of high blood pressure because of its anti-hypertensive properties in vivo (1). Recent studies suggest a potential use for Parkinson's disease (2).
Solubility	Soluble to 50 mM in DMSO and to 20 mM in ethanol
Source	Synthetic
Adr Code	Non-hazardous
Country Of Origin	Canada
Tarriff Code	3822.00.1090

Reference	1. Wada Y., Satoh K., Taira N. (1985) J Cardiovasc Pharmacol. 7(1): 190-196. 2. Chan C.S., et al. (2007) Nature. 447: 1081-1086.

Have you used this product?

Combination SKU	Supplier No.	Size	Your price	Quantity
BHB11900103-1	SIH-314-10MG	10 mg	$77		Add to Cart
BHB11900103-2	SIH-314-50MG	50 mg	$311		Add to Cart