I-CBP112 hydrochloride

Mfr.No.	T4247
Description	I-CBP112 is a selective inhibitor of the bromodomain-containing transcription factors. I-CBP112 (1 mM) has little activity against other bromodomains. I-CBP112 targets the CBP/p300 bromodomains. I-CBP112 significantly reduced the leukemia-initiating potential of MLL-AF9(+) acute myeloid leukemia cells in a dose-dependent manner in vitro and in vivo. Interestingly, I-CBP112 increased the cytotoxic activity of BET bromodomain inhibitor JQ1 as well as doxorubicin.
Molecular Formula	C27H37ClN2O5
Signaling Pathways	Chromatin/Epigenetic
Smiles	O(C(CH)1CN(C)CCC1)C2=C3C(=CC(=C2)C4=CC(OC)=C(OC)C=C4)CN(C(CC)=O)CCO3.Cl
Cas Number	2147701-33-3
Molecular Weight	505.05
Target	Epigenetic Reader Domain

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SKU	Supplier No.	Size	Your price
BHB20429076	T4247	1 mL	$471	Add to Cart
BHB20429076	T4247	1 mg	$83	Add to Cart
BHB20429076	T4247	2 mg	$148	Add to Cart
BHB20429076	T4247	5 mg	$249	Add to Cart
BHB20429076	T4247	25 mg	$773	Add to Cart
BHB20429076	T4247	50 mg	$1080	Add to Cart
BHB20429076	T4247	100 mg	$1460	Add to Cart