Hexafluoropropylene Oxide Dimer Acid

Mfr.No.	T83721
Description	Hexafluoropropylene oxide dimer acid (HFPO-DA), a perfluoroalkyl ether carboxylic acid (PFECA), shows diverse biological impacts across species. At 250 uM, it triggers apoptosis and enhances reactive oxygen species (ROS) levels in HepG2 cells. In hatchling chickens, HFPO-DA at a dosage of 4 mg/kg per egg notably decreases right ventricular wall thickness, accelerates heart rate, and promotes hepatic lipid accumulation, though these effects are mitigable by silencing the Ppara gene. It significantly reduces zebrafish embryo survival (LC50 = 7,651 mg/L). Additionally, when administered to pregnant dams at 250 mg/kg, it results in reduced average birthweight, decreased survival time, and lowered serum glucose levels, alongside increased serum cholesterol and triglyceride levels in neonatal rats. HFPO-DA has also been identified as a contaminant in sea and river water.
Molecular Formula	C6HF11O3
Signaling Pathways	Others
Smiles	O=C(C(OC(F)(C(F)(C(F)(F)F)F)F)(C(F)(F)F)F)O
Cas Number	13252-13-6
Molecular Weight	330.05
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20445431	T83721	1 g	$65		Add to Cart