GSK 3008348 hydrochloride is an integrin alphavbeta6 antagonist. The affinity (pIC50) for the human - a 6 protein in the Fluorescence Polarisation Assay for GSK 3008348 is 8.1, whereas its affinity in the cell Adhesion Assays was for alphanubeta6 (pIC50: 8.4); alphanubeta3 (pIC50: 6); alphanubeta5 (pIC50: 6.9); alphanubeta8 (pIC50: 7.7).