Dolastatin 10 trifluoroacetate

Mfr.No.	T22631
Description	Dolastatin 10 trifluoroacetate is a potent antimitotic polypeptide isolated from a marine animal and is developed as a potential antitumor agent. Dolastatin 10 is found to have an activity to inhibit tubulin polymerization (IC50: 1.2 uM). Besides that, it potently inhibits vincristine binding to tubulin (Ki: 1.4 uM in a non-competitive manner). Dolastatin 10 also shows a moderate effect on enhancing the binding of colchicines to tubulin. In addition, Dolastatin 10 has the inhibitory activity in tubulin-dependent GTP binding.
Alternative Names	Dolastatin 10 trifluoroacetate (110417-88-4 free base)
Molecular Formula	C44H69F3N6O8S
Signaling Pathways	Others
Smiles	CC(C)((C)(N(C((C)(/N=C(O)/(C)(N(C)C)((H))C(C)C)((H))C(C)C)=O)C)((H))(C)(OC)((H))CC(N1CCC(C)1((H))(C)(OC)((H))(C)(/C(O)=N/(C)(C2=NC=CS2)((H))CC3=CC=CC=C3)((H))C)=O)((H))C.FC(F)(C(O)=O)F
Molecular Weight	899.11
Target	Others

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SKU	Supplier No.	Size	Your price	Quantity
BHB20412455	T22631	1 mg	$477		Add to Cart
BHB20412455	T22631	5 mg	$1175		Add to Cart