Debio-0123

Mfr.No.	T9864
Description	Debio-0123 (WEE1-IN-5) is a potent, orally available and highly specific WEE1 inhibitor with an IC 50 in the low nanomolar range. Debio-0123 inhibits phospho-CDC2 which translated into an increase in DNA damage and premature entry into mitosis. Debio-0123 increases the antitumoral activity of Carboplatin in vivo whereas neither agent was active alone (1).
Alternative Names	WEE1-IN-5
Molecular Formula	C26H28Cl2N6O
Signaling Pathways	Cell Cycle/Checkpoint
Smiles	O=C1C=2C(=NC(NC3=CC(C)=C(C=C3)C4CCN(C)CC4)=NC2)N(C)CN1C5=C(Cl)C=CC=C5Cl
Cas Number	2243882-74-6
Molecular Weight	511.45
Target	Wee1

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SKU	Supplier No.	Size	Your price
BHB20447665	T9864	1 mL	$269	Add to Cart
BHB20447665	T9864	1 mg	$96	Add to Cart
BHB20447665	T9864	5 mg	$239	Add to Cart
BHB20447665	T9864	10 mg	$378	Add to Cart
BHB20447665	T9864	25 mg	$639	Add to Cart
BHB20447665	T9864	50 mg	$913	Add to Cart
BHB20447665	T9864	100 mg	$1230	Add to Cart