D-I03

Mfr.No.	T10936
Description	D-I03 is a selective RAD52 inhibitor with a Kd of 25.8 uM. D-I03 specifically inhibits RAD52-dependent single-chain annealing (SSA) and D-loop formation, with IC50 of 5 uM and 8 uM, respectively. D-I03 inhibited the growth of BRCA1 and BRCA2 deficient cells and inhibited the formation of damage-induced RAD52 foci, but does not effect on RAD51 foci induced by Cisplatin.
Alternative Names	DI03
Molecular Formula	C23H36N6S
Signaling Pathways	Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Smiles	CC=1C2=C(N=C(C1)N3CCN(CC)CC3)C=CC(NC(NCCN(CC)CC)=S)=C2
Cas Number	688342-78-1
Molecular Weight	428.64
Target	DNA/RNA Synthesis

Have you used this product?

SKU	Supplier No.	Size	Your price
BHB20401651	T10936	1 mL	$77	Add to Cart
BHB20401651	T10936	1 mg	$31	Add to Cart
BHB20401651	T10936	2 mg	$44	Add to Cart
BHB20401651	T10936	5 mg	$70	Add to Cart
BHB20401651	T10936	10 mg	$128	Add to Cart
BHB20401651	T10936	25 mg	$297	Add to Cart
BHB20401651	T10936	50 mg	$411	Add to Cart
BHB20401651	T10936	100 mg	$597	Add to Cart