CYC-116

Mfr.No.	T6458
Description	CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active against PKA, Akt/PKB, PKC, no effect on GSK-3alpha/beta, CK2, Plk1 and SAPK2A. Phase 1.
Alternative Names	CYC116
Molecular Formula	C18H20N6OS
Signaling Pathways	Chromatin/Epigenetic, Cell Cycle/Checkpoint, PI3K/Akt/mTOR signaling, Angiogenesis, MAPK, Tyrosine Kinase/Adaptors
Smiles	CC1=C(SC(N)=N1)C2=NC(NC3=CC=C(C=C3)N4CCOCC4)=NC=C2
Cas Number	693228-63-6
Molecular Weight	368.46
Target	S6 Kinase, Aurora Kinase, VEGFR, FLT, CDK

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SKU	Supplier No.	Size	Your price
BHB20434588	T6458	1 mL	$59	Add to Cart
BHB20434588	T6458	5 mg	$51	Add to Cart
BHB20434588	T6458	10 mg	$72	Add to Cart
BHB20434588	T6458	25 mg	$148	Add to Cart
BHB20434588	T6458	50 mg	$250	Add to Cart
BHB20434588	T6458	100 mg	$450	Add to Cart